// ************************************************************************************ // ** ** // ** ** // ** ** // ** ** // ** ** // ************************************************************************************ varLength = 10 var entryContent = new Array(varLength) entryContent[0] = " Generic Viagra relaxes muscles and increases blood flow to particular areas of the body.

Generic Viagra is used to treat erectile dysfunction (impotence) in men. Another brand of Generic Viagra is Revatio, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women.

Generic Viagra may also be used for other purposes not listed in this medication guide." entryContent[1] = " Do not take Generic Viagra if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Nitro-Bid, and others), isosorbide dinitrate (Dilatrate-SR, Isordil, Sorbitrate), and isosorbide mononitrate (Imdur, ISMO, Monoket). Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers").

Taking Generic Viagra with a nitrate medicine can cause a serious decrease in blood pressure, leading to fainting, stroke, or heart attack. During sexual activity, if you become dizzy or nauseated, or have pain, numbness, or tingling in your chest, arms, neck, or jaw, stop and call your doctor right away. You could be having a serious side effect of Generic Viagra." entryContent[2] = " Do not take Generic Viagra more than once a day. Allow 24 hours to pass between doses. Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.

Generic Viagra can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking Generic Viagra, most of whom also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoke or are over 50 years old. It is not clear whether Generic Viagra is the actual cause of vision loss.

Stop using Generic Viagra and get emergency medical help if you have sudden vision loss." entryContent[3] = " Generic Viagra can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking Generic Viagra, most of whom also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoke or are over 50 years old. It is not clear whether Generic Viagra is the actual cause of vision loss. Stop using Generic Viagra and get emergency medical help if you have sudden vision loss.

FDA pregnancy category B: This medication is not expected to be harmful to an unborn baby. Do not use Generic Viagra without telling your doctor if you are pregnant or plan to become pregnant during treatment. It is not known if Generic Viagra passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby." entryContent[4] = " Generic Viagra (compound UK-92,480) was synthesized by a group of pharmaceutical chemists working at Pfizer's Sandwich, Kent, research facility in England. It was initially studied for use in hypertension (high blood pressure) and angina pectoris (a symptom of ischaemic heart disease). The first clinical trials were conducted in Morriston Hospital in Swansea. Phase I clinical trials under the direction of Ian Osterloh suggested that the drug had little effect on angina, but that it could induce marked penile erections. Pfizer therefore decided to market it for erectile dysfunction, rather than for angina. The drug was patented in 1996, approved for use in erectile dysfunction by the US Food and Drug Administration on March 27, 1998, becoming the first oral treatment approved to treat erectile dysfunction in the United States, and offered for sale in the United States later that year. It soon became a great success: annual sales of Viagra in the period 1999–2001 exceeded $1 billion." entryContent[5] = " In 2000, Viagra sales accounted for 92 percent of the global market for prescribed erectile dysfunction pills. By 2007, Viagra's global share had plunged to about 50 percent[8] due to several factors, including the entry of Cialis and Levitra, along with several other generics and clones.

In February 2007, it was announced that Boots the Chemist would trial over the counter sales of Viagra in stores in Manchester, England. Men aged between 30 and 65 would be eligible to buy four tablets after a consultation with a pharmacist.

Pfizer's worldwide patents on Generic Viagra will expire in 2011–2013. The UK patent held by Pfizer on the use of PDE5 inhibitors (see below) as treatment of impotence was invalidated in 2000 because of obviousness; this decision was upheld on appeal in 2002." entryContent[6] = " The mechanism of action of Generic Viagra involves the release of nitric oxide (NO) in the corpus cavernosum of the penis. NO binds to the receptors of the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP), leading to smooth muscle relaxation (vasodilation) of the intimal cushions of the helicine arteries, resulting in increased inflow of blood and an erection. Robert F. Furchgott won the Nobel Prize in Physiology or Medicine in 1998 for his discovery and analysis of endothelium-derived relaxing factor, a key part of the NO mechanism of action.

Generic Viagra is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum. The molecular structure of Generic Viagra is similar to that of cGMP and acts as a competitive binding agent of PDE5 in the corpus cavernosum, resulting in more cGMP and better erections.[14] Without sexual stimulation, and therefore lack of activation of the NO/cGMP system, Generic Viagra should not cause an erection. Other drugs that operate by the same mechanism include tadalafil (Cialis) and vardenafil (Levitra).
Generic Viagra is metabolised by liver enzymes and excreted by both the liver and kidneys. If taken with a high-fat meal, absorption is reduced; the time taken to reach the maximum plasma concentration increases by around one hour, and the maximum concentration itself is decreased by nearly one-third." entryContent[7] = " Generic Viagra's popularity with young adults has increased over the years. Generic Viagra's trade name "Viagra" is widely recognized in popular culture, and the drug's association with treating erectile dysfunction has led to its recreational use. The reasons behind such use include the belief that the drug increases libido, improves sexual performance, or permanently increases penis size. Studies on the effects of viagra when used recreationally are limited, but suggest that it has little effect when used by those not suffering from erectile dysfunction, and having sex within a stable relationship. In one study, a 25mg dose was shown to cause no significant change in erectile quality, but did reduce the post-ejaculatory refractory time. This study also noted a significant placebo effect in the control group.

Unprescribed recreational use of Generic Viagra and other PDE-5 Inhibitors is noted as particularly high among users of illegal drugs. Generic Viagra is sometimes used to counteract the effects of other substances, often illicit. Some users mix it with methylenedioxymethamphetamine (MDMA, ecstasy), other stimulants, or opiates in an attempt to compensate for the common side-effect of erectile dysfunction, a combination known as "sextasy," "rockin' and rollin'," or "trail mix." Mixing with amyl nitrite is particularly dangerous, and is potentially fatal." entryContent[8] = " Acetildenafil is a structural analogue of Generic Viagra, one of the PDE5 inhibitors found in a number of "herbal" aphrodisiac products sold over-the-counter. This class of analogues have not undergone any of the rigorous testing that drugs like Generic Viagra have passed, and thus have an unknown side-effect profile.

Some attempts have been made to ban these drugs, but progress has been slow so far, as, even in those jurisdictions that have laws targeting designer drugs, the laws are drafted to ban analogues of illegal drugs of abuse, rather than analogues of prescription medicines. However, at least one court case has resulted in a product being taken off the market." entryContent[9] = " The British press portrayed Peter Dunn and Albert Wood as the inventors of Sildenafil Citrate, a claim that Pfizer disputes. Their names are even on the manufacturing patent application drug, but Pfizer claims this is only for convenience.

Even though Generic Viagra is available only by prescription from a doctor in the U.S., it was advertised directly to consumers on U.S. TV (famously being endorsed by former United States Senator Bob Dole and soccer star Pelè). Numerous sites on the Internet offer Viagra for sale after an "online consultation", often a simple web questionnaire. The "Viagra" name has become so well known that many fake aphrodisiacs now call themselves "herbal Viagra" or are presented as blue tablets imitating the shape and colour of Pfizer's product. Viagra is also informally known as "Vitamin V", "the Blue Pill", as well as various other nicknames." var randomNumber = Math.random() randomNumber *= varLength randomNumber = parseInt(randomNumber) if(isNaN(randomNumber)) randomNumber = 0 else randomNumber %= varLength selectedContent = entryContent[randomNumber] document.write (selectedContent)